She was born in 1961 in Rosario, Santa Fe, Argentina.

She is an art professor, graduated in 1984 from Prilidiano Pueyrredón National School of Fine Arts, in Buenos Aires. In 1987 she was part of Grupo de la X. From 1990 until 2001, she worked in the Clothing and Textile Department of Skific/Saltzman at the National University of Buenos Aires. Between 1996 and 2003, she was professor of the third year in Painting at Prilidiano Pueyrredón National School of Fine Arts.

She has participated in international art fairs and biennials, such as the Cuenca Biennial in Ecuador (1998) and the Panama Biennial (2013). She took part in a workshop organized by Progreso Foundation, sponsored by Rockefeller Foundation.

She received the Grant for Artistic Creation from Antorchas Foundation in 1989 and 1999, same year in which she won the Grant from the Argentine National Arts Fund.

In 2018 she received the Achievement Award from the María Calderón de la Barca Foundation; in 2016 the First Prize for Drawing from the National Visual Arts Salon and the Acquisition Prize from the National Painting Salon; in 2015 the First Prize for Panting from the Buenos Aires Province Bank; in 2003 a Special Mention Award in the Ibero-American Painting Contest from Buenos Aires; in 1998 the Leonardo Award for Artist of the Year from the National Museum of Fine Arts in Buenos Aires; in 1997 the Honorable Mention Award from Fortabat Foundation and MNBA, and the First Prize from Federico Klemm Foundation.

Among her exhibitions are: ‘El beso dorado del bosque’ in Calvaresi Gallery (2018); ‘Sonidos Mentales’ in Diego Obligado Art Gallery (2017); ‘Vértigo de la contemplación’ in Matilde Bensignor Gallery (2017); ‘Antoniadis’ in Hotel Brick Buenos Aires (2015); ‘Ocaso’, installation in OSDE Foundation, Buenos Aires (2015); ‘Incesantes Avalorios’ in Arteconsult Gallery, Panama (2013); ‘Contrastes. Matilde Marín – Carolina Antoniadis’ in Galería del Infinito (2013); ‘Carolina Antoniadis’ in Diego Obligado Art Gallery (2012); ‘Botanical Suites’ in Expressiones Cultural Center in New London, Connecticut, EUA (2012); ‘Jugenstill’ in Galería del Infinito (2011); ‘Muy Antoniadis’, a retrospective in San José Olavarría Cultural Center (2011); ‘Bio-Redes’ in Arteconsult Gallery and Yaco García, Panama (2011); ‘Bio-Enlaces’ in Arteconsult Gallery and Yaco García (2008); ‘Domus-referencial’ in Recoleta Cultural Center (2006); ‘Pluscuamperfecto’ in Galería del Infinito (2006); ‘El Delito de la Belleza. Anthological Selection (1986-2003) in Parque de España Cultural Center, Rosario (2003).

Her works are part of international and official collections, in the Buenos Aires Museum of Modern Art, Castagnino+Macro Museum, Tandil Fine Arts Museum, Amalia Lacroze de Fortabat Foundation, Federico Klemm Foundation, Argentine Central Bank Foundation, Banco Hipotecario Foundation, Aerolíneas Argentinas Foundation, Telefónica Foundation, Banco Patricios Foundation, Buenos Aires Province Bank Foundation, Argentine National Bank Pinacotheca, Suterh Union, Avon Foundation.

She lives and works in Buenos Aires.